Understanding donor heart preservation: Cellular mechanisms and clinical outcomes

Yaagnik Kosuri, Morgan K Moroi, Sebastian Johannes Bauer, Anthony Campbell, Arianna Adamo, Cary Karcher, Brianna Costa, Claire Kho, Ephraim Jacobson, Shawn Lee, Payam Akhyari, Koji Takeda, Giovanni Ferrari, Department of Surgery, Columbia University, New York, Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, Fondazione Ri

Perfusion

Published online on September 09, 2025

Abstract

Perfusion, Volume 41, Issue 5, Page 547-558, July 2026.
Static cold storage (SCS) on ice has remained the gold standard preservation method for heart transplantation, and prolonged cold ischemia outside the typical 4–6 hour window is associated with an increased risk of primary graft dysfunction – a ...