Temporal trends and risk factors for bleeding and thrombosis in pediatric ECMO: A multicenter cohort study
Kevin J. Doré,
Carlton M. Kelly,
Timothy T. Cornell,
Lindsey K. Rasmussen,
Shelby Burk,
Laura L. Loftis,
Christine Allen,
Melania M. Bembea,
Brian M. Boville,
Jamie Furlong-Dillard,
Santosh Kaipa,
Bridget Norton,
Heather Viamonte,
Linda Wallenkamp,
Ahmed Said,
Marie E. Steiner,
Matthew P. Malone,
Aaron Kline,
Daniel Tawfik,
Department of Pediatrics,
Division of Critical Care Medicine,
Stanford University School of Medicine,
Department of Psychiatry and Behavioral Sciences,
Stanford University School of Medicine,
Division of Critical Care Medicine,
Department of Pediatrics,
Texas Children,
s Hospital and Baylor College of Medicine,
Division of Pediatric Critical Care,
University of Oklahoma Health Sciences Center,
Oklahoma City,
Department of Anesthesiology and Critical Care Medicine,
Johns Hopkins University School of Medicine,
Pediatric Critical Care Medicine,
Helen DeVos Children,
s Hospital,
Grand Rapids,
Division of Pediatric Critical Care Medicine,
Department of Pediatrics,
Norton Children,
s Hospital and University of Louisville School of Medicine,
Department of Pediatrics,
s Nebraska and University of Nebraska Medical Center,
s Healthcare of Atlanta and Emory University,
s Wisconsin and Medical College of Wisconsin,
Division of Pediatric Critical Care,
Department of Pediatrics,
and Institute of Informatics,
Data Science and Biostatistics,
Washington University in St Louis School of Medicine,
St Louis,
Divisions of Pediatric Hematology,
Oncology and Pediatric Critical Care,
Department of Pediatrics,
University of Minnesota,
Division of Critical Care Medicine,
Department of Pediatrics,
University of Arkansas for Medical Sciencesand Arkansas Children,
s Hospital,
Little Rock,
Department of Biomedical Data Science,
Stanford University
Perfusion
Published online on July 31, 2025
Perfusion, Volume 41, Issue 4, Page 401-413, May 2026.
IntroductionBleeding and thrombosis are major causes of morbidity and mortality in pediatric extracorporeal membrane oxygenation (ECMO), yet their evolving, time-dependent risks remain poorly defined. This study evaluated clinical predictors of bleeding ...