Comparison of the myocardial protection efficacy between Del Nido cardioplegia and HTK cardioplegia in adult cardiac valve surgery

Yinying Xue, Shangyu Chen, Mengqiu Jiang, Jilai Xiao, Xiao Shen, Huan Xu, Liang Hong, Xiaochun Song, Cui Zhang, Department of Intensive Care Unit of Nanjing First Hospital, Nanjing Medical University

Perfusion

Published online on April 20, 2026

Abstract

Perfusion, Ahead of Print.
BackgroundWith the advancement of cardiopulmonary bypass technology, several cardioplegia solutions have been introduced, including del Nido cardioplegia (DN) and histidine-tryptophan-ketoglutarate (HTK) solutions. However, the cardioplegia solution with ...