Time-dose response of oxygen delivery during cardiopulmonary bypass in mitral valve surgery: does surgical approach matter?

Maximilian Reisinger, Mateusz Kachel, Chunhui Wang, Luigi Pirelli, Arnar Geirsson, Michael Argenziano, Paul Kurlansky, Christine Chan, Kenmond Fung, James Beck, Isaac George, Division of Cardiac, Vascular Surgery, New York-Presbyterian Hospital, Columbia University Medical Center, New York, Clinical Perfusion, New York-Presbyterian Hospital, Columbia University Medical Center, New York

Perfusion

Published online on July 16, 2025

Abstract

Perfusion, Volume 41, Issue 3, Page 319-328, April 2026.
IntroductionIncreased time-dose-response (TDR) of suboptimal oxygen delivery (DO2) during cardiopulmonary bypass (CPB) has been associated with increased postoperative complications. The impact of surgical approach - minimally invasive vs. median ...