Mitochondrial-related pathogenic genes in varicose veins: A multi-omics Mendelian randomization study

Xiaoyun Tan, Zhenyin Liu, Kunshan Chen, Dan Li, Jiejun Xia, Chuanqiang Niu, Haibo Li, Jianzhong Huang, Department of Interventional Radiology , Vascular Anomalies, Guangzhou Women and Children, s Medical Center, Guangzhou Medical University, Department of Ultrasound Medicine, Liwan Central Hospital of Guangzhou

Phlebology: The Journal of Venous Disease

Published online on November 10, 2025

Abstract

Phlebology, Volume 41, Issue 6, Page 491-499, July 2026.
ObjectivesThe dysfunction of mitochondria has been associated with the development of varicose veins (VV), but the specific mitochondrial-related genes and their roles in VV have not been fully elucidated. We employed Mendelian randomization (MR) and ...