Relational Aspects to Screening-Associated Distress Among Individuals With Li-Fraumeni Syndrome: “The All-Clear for Me Is Good. The All-Clear for My Kids Is Great”

Chloe O. Huelsnitz, Allison Werner-Lin, Rowan Forbes Shepherd, Paul K. J, Payal P. Khincha, Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, School of Social Policy and Practice, University of Pennsylvania

Qualitative Health Research

Published online on September 15, 2025

Abstract

Qualitative Health Research, Ahead of Print.
Screening-associated distress, or “scanxiety,” is a recognized challenge for individuals at risk of cancer diagnosis or recurrence, particularly for those with Li-Fraumeni syndrome (LFS), a cancer predisposition syndrome with high lifetime cancer risks. ...