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A hybrid prior Bayesian method for combining domestic real-world data and overseas data in global drug development

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Statistical Methods in Medical Research: An International Review Journal

Published online on

Abstract

Statistical Methods in Medical Research, Volume 35, Issue 3, Page 552-570, March 2026.
BackgroundHybrid clinical trial design integrates traditional randomized controlled trials (RCTs) with real-world data (RWD), aiming to enhance trial efficiency through dynamic incorporation of external data (External trial data and RWD). However, ...