Efficacy and safety of glucocorticoids for acute drug-induced liver injury with hyperbilirubinemia: protocol of a multicenter randomized controlled trial

Qianqian Li, Yong Lin, Xin Zeng, Lu Zhou, Fengmei Wang, Qing Ye, Yanjing Gao, Lianyi Guo, Jin Zhu, Jia Li, Yiling Li, Lichun Shao, Yiling Hu, Jiancun Xiao, Ao Jia, Dongsheng Wang, Lijun Chang, Jian Wang, Jianzhong Zhang, Ran Wang, Fei Gao, Qinke Wu, Pingfang Hu, Changpeng Zhu, Lingyan Cai, Ying Ran, Yueyue Li, Jiayuan Zhang, Yupeng Ran, Chunyan Wang, Ningning Wang, Jian Zhang, Xiehua Zhang, Juan Li, Jing Sun, Yunxiang Chu, Yali Ma, Tingting Wang, Zheng Zheng, Yue Shen, Xingshun Qi, Weifen Xie

Therapeutic Advances in Gastroenterology

Published online on April 26, 2026

Abstract

Therapeutic Advances in Gastroenterology, Volume 19, January-December 2026.
Background:Drug-induced liver injury (DILI) can lead to potentially fatal complications, such as acute liver failure and even death. In clinical practice, glucocorticoids have been considered in some cases of DILI, especially those with ...