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Integrating intracranial hypofractionated radiotherapy with immunotherapy for melanoma brain metastases: therapeutic impact and immune modulation

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Therapeutic Advances in Medical Oncology

Published online on

Abstract

Therapeutic Advances in Medical Oncology, Volume 18, January-December 2026.
Background:Combined radiotherapy and immunotherapy can enhance antitumor efficacy, but its effects on melanoma brain metastases (MBM) remain unclear.Objectives:To evaluate the intracranial efficacy, safety, and exploratory immune biomarkers of ...