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Heparin-Induced Thrombocytopenia With a False Negative Anti-PF4 Assay

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Vascular and Endovascular Surgery

Published online on

Abstract

Vascular and Endovascular Surgery, Volume 60, Issue 4, Page 358-360, May 2026.
Background:Heparin-induced thrombocytopenia (HIT) is an acquired prothrombotic state from anti-heparin platelet-factor 4 (PF4) mediated activation of platelets. Anti-PF4 assay is used to screen for HIT due to high sensitivity and negative predictive ...