Aging diminishes thymic output, reduces naive T cells, promotes memory T-cell accumulation, and impairs thymic regeneration

Daria M. Konovalova, Madison D. Cooper, Shuli Huang, Danielle X. Shane, Jordyn S. Mulhern, Ying Ann Chiao, Sarah Y. Yuan, Yonggang Ma

Published online on May 11, 2026

Abstract

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Volume 330, Issue 6, Page R609-R622, June 2026.