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Phenotype-driven management in ileocecal Crohn’s disease: a narrative review with a proposed research framework

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Therapeutic Advances in Gastroenterology

Published online on

Abstract

Therapeutic Advances in Gastroenterology, Volume 19, January-December 2026.
The management of localized ileocecal Crohn’s disease (CD) requires balancing escalation of medical therapy against early surgical resection. While clinical phenotyping guides initial management, standard assessments often fail to distinguish reversible ...