trans-Chalcone protects against high-fat diet-induced kidney injury in rats by regulating the miR-874/TLR4 pathway
Published online on May 08, 2026
Abstract
Nutrition and Health, Ahead of Print.
BackgroundChronic high-fat diet (HFD) consumption is linked to chronic kidney disease. Toll-like receptor 4 (TLR4) promotes pro-fibrotic and pro-inflammatory pathways in the kidney. It is directly inhibited by renal miR-874.trans-Chalcone has protective ...
BackgroundChronic high-fat diet (HFD) consumption is linked to chronic kidney disease. Toll-like receptor 4 (TLR4) promotes pro-fibrotic and pro-inflammatory pathways in the kidney. It is directly inhibited by renal miR-874.trans-Chalcone has protective ...