Hepatoprotective effects and mechanistic basis of cinnamaldehyde in preclinical liver disease models: A systematic review

Jueliang Li, Wei Chen, Qianhui Lai, Honglei Zhao, Shenzhen Nanshan Medical Group Headquarter, The Eighth Affiliated Hospital, Sun Yat-sen University, Fuwai Shenzhen Hospital, Chinese Academy of Medical Sciences

Journal of International Medical Research

Published online on May 14, 2026

Abstract

Journal of International Medical Research, Volume 54, Issue 5, May 2026.
ObjectiveTo systematically evaluate the preclinical evidence on the hepatoprotective effects of cinnamaldehyde and summarize the key biological mechanisms underlying its actions across different liver disease settings.MethodsA systematic search was ...