Global trends, epidemiological patterns, and disability burden of metabolic dysfunction-associated steatotic liver disease–related cirrhosis from 1990 to 2021: A comprehensive analysis of the Global Burden of Disease study

Xuli Wang, Bingwei Wang, Department of Otorhinolaryngology, Head and Neck and Thyroid Surgery, s Hospital of Pengzhou, Department of Cardiology, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Southwest Medical University, Basic Medicine Research Innovation Center for Cardiometabolic Diseases, Ministry of Education, Southwest Medical University, Nucleic Acid Medicine, Key Laboratory of Luzhou, Southwest Medical University

Journal of International Medical Research

Published online on May 14, 2026

Abstract

Journal of International Medical Research, Volume 54, Issue 5, May 2026.
ObjectivesTo assess long-term global trends in the burden of metabolic dysfunction-associated steatotic liver disease–related cirrhosis and develop a simplified, waist circumference–based prediction model for early identification of individuals at risk of ...