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Imatinib-Induced Hemorrhage in the Corpus Luteum Is Attenuated in Pseudopregnant and Hypophysectomized Rats

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Toxicologic Pathology

Published online on

Abstract

Toxicologic Pathology, Ahead of Print.
Imatinib, a tyrosine kinase inhibitor that targets BCR-ABL, platelet-derived growth factor receptors (PDGFRs), and c-KIT, is known to cause rare ovarian hemorrhagic events. This study investigated the mechanisms underlying imatinib-induced hemorrhage in ...