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Multisystem pathology in chronic variable stress: gut–liver–brain axis disruption and the therapeutic promise of magnesium-L-theanine

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Therapeutic Advances in Endocrinology and Metabolism

Published online on

Abstract

Therapeutic Advances in Endocrinology and Metabolism, Volume 17, January-December 2026.
Chronic variable stress (CVS) is a well-established translational model that captures the unpredictability, persistence, and cumulative burden of long-term stress exposure. Through repeated application of heterogeneous mild-to-moderate stressors in a non-...