Tannic acid–metal single-cell nano-coatings regulate bone mesenchymal stem cell fate through ion-specific pericellular microenvironments

Jia Wu, Renguo Gong, Yongmei Wen, Shan Kong, Pan Yang, Xia Deng, Department of Stomatology, The Second Affiliated Hospital of Chengdu Medical College, Nuclear Industry , Department of Stomatology, The First Affiliated Hospital of Chengdu Medical College, Department of Prosthodontics, The Affiliated Stomatological Hospital of Southwest Medical University, Department of Stomatology, First People, s Hospital of Jintang County

Journal of Biomaterials Applications

Published online on June 03, 2026

Abstract

Journal of Biomaterials Applications, Ahead of Print.
Bone and cartilage regeneration remains a major clinical challenge due to the limited intrinsic repair capacity of musculoskeletal tissues. Biomaterial strategies capable of regulating stem cell behavior at the single-cell level offer new opportunities ...