Treatment of bacterial keratitis in mouse using Ag nanoparticles suspension

Chang Liu, Zhezhen Wei, Lanlan Wang, Qing Zhang, Dongwei Liu, Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Institute of Health and Medicine, Hefei Comprehensive National Science Center, Department of Ophthalmology, Shannan People, s Hospital of Tibet

Journal of Biomaterials Applications

Published online on May 28, 2026

Abstract

Journal of Biomaterials Applications, Ahead of Print.
This study aimed to develop a novel topical treatment for Pseudomonas aeruginosa (P. aeruginosa)-induced bacterial keratitis (BK) using silver nanoparticles (Ag NPs), addressing critical limitations of current antibiotics, such as poor ocular penetration ...