Safety of prolonged anticoagulation-free venovenous ECMO management beyond 72 hours in post-traumatic ARDS: A single-center retrospective cohort study

Changsung Han, Seunghwan Song, Soojin Lee, Na Hyeon Lee, Seon Hee Kim, Department of Thoracic and Cardiovascular Surgery, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Republic of Korea, Department of Thoracic and Cardiovascular Surgery, Seoul Regional Trauma Center, National Medical Center, Republic of Korea, Department of Trauma and Surgical Critical Care, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Republic of Korea

Perfusion

Published online on June 17, 2026

Abstract

Perfusion, Ahead of Print.
IntroductionStandard anticoagulation protocols for patients with trauma-related acute respiratory distress syndrome (TR-ARDS) undergoing venovenous extracorporeal membrane oxygenation (VV-ECMO) are often inapplicable due to high bleeding risks. This study ...