Comparison of pharmacovigilance and mechanism analysis of the vascular toxicity caused by platin-based chemotherapy: integration of FAERS analysis, network pharmacology, and endothelial validation
Therapeutic Advances in Drug Safety
Published online on June 03, 2026
Abstract
Therapeutic Advances in Drug Safety, Volume 17, January-December 2026.
Background:Understanding of the possible vasoactive toxicities associated with platinum‑containing chemotherapeutic drugs for solid tumors remains limited.Objectives:This study comprehensively identifies the vessel-threatening effects of cisplatin (CDDP), ...
Background:Understanding of the possible vasoactive toxicities associated with platinum‑containing chemotherapeutic drugs for solid tumors remains limited.Objectives:This study comprehensively identifies the vessel-threatening effects of cisplatin (CDDP), ...