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Cytokine release syndrome in solid tumours: mechanism-based therapeutic strategies for prevention and management

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Therapeutic Advances in Medical Oncology

Published online on

Abstract

Therapeutic Advances in Medical Oncology, Volume 18, January-December 2026.
Cytokine release syndrome (CRS) represents a spectrum of immune hyperactivation initiated by rapid T-cell engagement and amplified through innate immune cells, particularly monocytes and macrophages, with downstream cytokine cascades driving endothelial ...