Benzodiazepine receptor agonist deprescribing principles for long-term use and dependence: modified Delphi recommendations from a multi-disciplinary expert panel

Jaden Brandt, Nicole Lamberson, Jolene Bressi, Alexis Ritvo, Janice Curle, Josef Witt-Doerring, Marjorie DeWert, Steven Wright, Mark Horowitzon behalf of the Alliance for Benzodiazepine Best Practices and Benzodiazepine Information Coalition

Therapeutic Advances in Psychopharmacology

Published online on June 10, 2026

Abstract

Therapeutic Advances in Psychopharmacology, Volume 16, January-December 2026.
Background:Benzodiazepine receptor agonists (BZRA) are frequently tapered because of risk of dependence and hazards of use in ageing. Standard tapering protocols may fail or result in harm from improper utilization of pharmacologic principles, lack of ...