Adeno-Associated Virus Gene Therapy: Is There a Risk of Insertional Mutagenesis?
Published online on May 31, 2026
Abstract
Toxicologic Pathology, Ahead of Print.
Adeno-associated virus (AAV) gene therapy has received approvals for the treatment of a number of rare monogenic disorders. There are questions surrounding the natural history of recombinant AAV (rAAV) vectors, which could provide insights into durability ...
Adeno-associated virus (AAV) gene therapy has received approvals for the treatment of a number of rare monogenic disorders. There are questions surrounding the natural history of recombinant AAV (rAAV) vectors, which could provide insights into durability ...