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Hemangiosarcomas in Intercostal Brown Adipose Tissues of the Sternum Induced by Urethane in TgrasH2 Mice

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Toxicologic Pathology

Published online on

Abstract

Toxicologic Pathology, Ahead of Print.
Urethane has been used as a positive control material for carcinogenicity studies in the TgrasH2 mouse that is a valuable model in pre-clinical safety investigations. This article describes the incidence of hemangiosarcomas (HSAs) in the intercostal ...