["Journal of Clinical Psychology, EarlyView. ", "\nABSTRACT\n\nObjectives\nAlthough the prevalence of affective comorbidities with eating disorders (ED) has been well established, the three‐way relation between ED, depression, and anxiety symptoms has not been explored in an intensive adolescent treatment setting.\n\n\nMethods\nThis study analyzed data from a sample of teenage girls with anorexia nervosa in higher levels of care (n = 457) to assess the relations between changes in ED symptoms, depression, and anxiety over the course of ED treatment.\n\n\nResults\nThis study demonstrated that improvements in depression and anxiety are significantly associated with improvement in ED symptoms.\n\n\nConclusion\nFindings support the importance of routine assessments for depression and anxiety among adolescents with anorexia nervosa in higher levels of care and a transdiagnostic approach to treatment that addresses shared underlying mechanisms. Future research that aims to uncover mediators and moderators of these relations is warranted to enhance clinical efforts.\n"]