["American Journal of Human Biology, Volume 38, Issue 6, June 2026. ", "\nABSTRACT\n\nObjectives\nResearch in Western samples has repeatedly demonstrated a link between exposure to nature and natural stimuli and improved health. We sought to test these relationships in a sample of Indigenous Wixárika, whose traditional worldview is nature‐based and conceives of all life as interconnected, in contrast to Western norms.\n\n\nMethods\nA total of 127 Wixárika adults (68.5% female, mean age = 33.6 years) were recruited from Guadalajara and a rural community, as part of a larger study on Wixárika health. Participants completed surveys including a Connectedness to Nature (CNS) scale, self‐reported mental and physical health, and frequency of participation in traditional ceremonies, a proxy of adherence to a traditional worldview. Firth logistic regression was used to model the effects of CNS and ceremony participation on both health measures.\n\n\nResults\nRural participants had worse health, but greater CNS scores (p < 0.001 for both) and more frequent ceremony participation than urban participants. Higher CNS scores were associated with better mental health (OR = 4.94, 95% CI = 1.60–16.45, p = 0.005) in rural participants, with no effect on either health measure in urban participants.\n\n\nConclusion\nResults partially supported our prediction that greater CNS would be associated with better health. Notably, the only statistically significant relationship was in rural Wixáritari. The effects of CNS on health may diminish in generally healthy individuals (i.e., Guadalajara residents). Future work should probe this possibility further. This work calls attention to potential discrepancies in the health/nature nexus in non‐Western contexts and the need to explore different cultural understandings of nature.\n\n"]