Elevated Tissue Factor and TFPI Levels in Acute COPD Exacerbations: A Prospective Comparison With Stable COPD and Healthy Controls

Fang Shen, Miao Yang, Mu-Dan He, Xiao-Wen Hu, Yu-Ping Duan, Zhi-Wen Nie, Xing-Jing Li, Department of Respiratory and Critical Care Medicine, Wusong Central Hospital in Baoshan District, Community Health Service Center, Yanghang Town, Baoshan District, Department of Laboratory, Wusong Central Hospital in Baoshan District

Clinical and Applied Thrombosis/Hemostasis

Published online on July 17, 2026

Abstract

Clinical and Applied Thrombosis/Hemostasis, Volume 32, January-December 2026.
PurposeThis prospective study aimed to evaluate tissue factor (TF) and tissue factor pathway inhibitor (TFPI) as potential biomarkers of hypercoagulability in patients with acute exacerbation of COPD (AECOPD), compared to stable COPD patients and healthy ...