Usefulness of Clot Waveform Analysis-Activated Thromboplastin Time (APTT) for Diagnosing Thrombotic Diseases

Hiyori Ikeda, Hideo Wada, Nobuo Arai, Masafumi Kimura, Jun Masuda, Nobuo Ito, Nozomi Ikeda, Yuhuko Ichikawa, Motoko Tanaka, Kaoru Azuma, Minoru Ezaki, Katsuya Shiraki, Motomu Shimaoka, Hideto Shimpo, Department of Central Laboratory, Mie Prefectural General Medical Center, Department of General and Laboratory Medicine, Mie Prefectural General Medical Center, Sysmex Corporation, Department of Cardiology, Mie Prefectural General Medical Center, Department of Neurology, Mie Prefectural General Medical Center, Department of Molecular Pathobiology and Cell Adhesion Biology, Mie University Graduate School of Medicine, Mie Prefectural General Medical Center

Clinical and Applied Thrombosis/Hemostasis

Published online on June 22, 2026

Abstract

Clinical and Applied Thrombosis/Hemostasis, Volume 32, January-December 2026.
ObjectiveClot waveform analysis (CWA)-activated partial thromboplastin time (APTT) has been used for the diagnosis of bleeding disorders. In addition to previous parameters such as Min 1, Min 2, and Max 2, we analyzed the area under the curve (AUC) of CWA ...