Hydrogen ion (pH) and gas behavior during deep hypothermic cardiopulmonary bypass: Physiology and clinical implications

Sylvain Diop, Jacques Thes, Maria Cristina Kassab, Roman Mounier, Department of Anesthesiology, Marie Lannelongue Hospital, Le Plessis Robinson, Cardiothoracic Intensive Care Unit, Marie Lannelongue Hospital, Le Plessis Robinson, Cardiothoracic Perfusion Team, Marie Lannelongue Hospital, Le Plessis Robinson, Department of Anaesthesiology and Critical Care, Avicenne Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris XIII

Perfusion

Published online on June 23, 2026

Abstract

Perfusion, Ahead of Print.
Deep hypothermic cardiopulmonary bypass (CPB) is used in selected procedures such as pulmonary endarterectomy (PEA) and aortic arch repair. Hypothermia induces metabolic and physicochemical changes that affect hydrogen ion concentration ([H+]), ...