A comparison of methods for designing hybrid type 2 cluster-randomized trials with continuous effectiveness and implementation endpoints
Statistical Methods in Medical Research: An International Review Journal
Published online on June 24, 2026
Abstract
Statistical Methods in Medical Research, Volume 35, Issue 7, Page 1493-1517, July 2026.
Hybrid type 2 studies are gaining popularity for their ability to assess both implementation and health outcomes as co-primary endpoints. Often conducted as cluster-randomized trials (CRTs), five design methods can validly power these studies:p-value ...
Hybrid type 2 studies are gaining popularity for their ability to assess both implementation and health outcomes as co-primary endpoints. Often conducted as cluster-randomized trials (CRTs), five design methods can validly power these studies:p-value ...