Sex-specific risk factors for genital infections associated with SGLT2 inhibitors in type 2 diabetes: a retrospective cohort study and disproportionality analysis using JADER

Ayami Kajiwara-Morita, Sawa Kugimoto, Kentaro Oniki, Akira Yoshida, Noboru Kurinami, Tomoko Suzuki, Fumio Miyamoto, Kunio Hieshima, Seigo Sugiyama, Keizo Kajiwara, Katsunori Jinnouchi, Hideaki Jinnouchi, Junji Saruwatari

Therapeutic Advances in Drug Safety

Published online on July 21, 2026

Abstract

Therapeutic Advances in Drug Safety, Volume 17, January-December 2026.
Background:Genital infections are notable adverse events that may lead to nonadherence to or discontinuation of sodium-glucose cotransporter 2 (SGLT2) inhibitors, essential agents in the management of type 2 diabetes (T2D). Although sex differences in ...