Relationship between serum clozapine to N-desmethyclozapine ratio and cognitive performance among people with treatment-resistant schizophrenia

Manshi RaiRockingham General Hospital, Haileab Fekadu WoldeBiostatistics Team, The Kids Research Institute, Western Australia, Alexander Panickacheril JohnDivsion of Psychiatry, Medical School, The University of Western Australia , Bentley Health Service

Australasian Psychiatry

Published online on July 17, 2026

Abstract

Australasian Psychiatry, Ahead of Print.
ObjectiveWe evaluated the relationship of serum clozapine and N-desmethyl clozapine (NDMC) and their ratio and cognition among people with treatment-resistant schizophrenia (TRS), an area that has been sub-optimally researched.MethodsCognitive function ...