Integrated Ultrasound Localization Microscopy and Multi-Omics for Mechanism-Driven Stratification of Azoospermia

Chujun Ye, Qijie Lu, Keke Yang, Maoyao Li, Chao Feng, Lei Chen, Department of Ultrasound in Medicine, Shanghai Sixth People, s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Key Laboratory of Neuro-Ultrasound for Diagnosis and Treatment, Department of Reproductive Medicine, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Key Laboratory of Embryo Original Disease

American Journal of Men's Health

Published online on July 30, 2026

Abstract

American Journal of Men's Health, Volume 20, Issue 4, July-August 2026.
Accurate differentiation between non-obstructive azoospermia (NOA) and obstructive azoospermia (OA) is crucial for therapeutic decision-making, yet current diagnostic approaches predominantly depend on invasive testicular biopsy. Herein, we establish a ...