HLX07, a novel anti-EGFR antibody, for locally advanced and metastatic cutaneous squamous cell carcinoma: an open-label, multicenter, phase II trial

Changxing Li, Kang Zeng, Dongyuan Zhu, Zhengfu Fan, Yong Chen, Yu Chen, Yong Li, Mingkai Ji, Ping Duan, Juan Su, Jilong Yang, Yang Tang, Mingjun Zhang, Siyang Wang, Gengsheng Yu, Yisheng Huang, Rongyi Chen, Xuhui Hu, Futang Yang, Haoyu Yu, Qingyu Wang, Jing Li, Jun Zhu

Therapeutic Advances in Medical Oncology

Published online on August 04, 2026

Abstract

Therapeutic Advances in Medical Oncology, Volume 18, January-December 2026.
Background:Cutaneous squamous cell carcinoma (CSCC) accounts for 20% of all cutaneous cancers. Systemic treatment options for advanced CSCC (aCSCC) include immunotherapy, chemotherapy, and epidermal growth factor receptor (EGFR)-targeted therapy, although ...