Lung organoids as emerging models in idiopathic pulmonary fibrosis research: Current applications, challenges, and future directions

Yuxin Jia, Wenxian Liu, Weifeng Tang, Silin Ou, Na Wang, Ming Dong, Ying Wei, Department of Integrative Medicine, Huashan Hospital Fudan University, Institute for the Modernization of Traditional Chinese Medicine, er University, Department of Respiratory Medicine, Second Affiliated Hospital of Yunnan University of Chinese Medicine, Department of Integrative Medicine, s Hospital of Fudan University, Department of Rehabilitation Medicine, Gumei Community Health Center of Minhang District of Shanghai, Institutes of Integrative Medicine, Fudan University

Therapeutic Advances in Respiratory Disease

Published online on August 04, 2026

Abstract

Therapeutic Advances in Respiratory Disease, Volume 20, January-December 2026.
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with progressive, irreversible scarring and a median survival of approximately 3–5 years after diagnosis. Current therapies (nintedanib, pirfenidone) modestly slow progression but do not ...