Deep versus moderate hypothermia in pediatric cardiac surgery: Systematic review and meta-analysis of early postoperative outcomes

Ioannis Zoupas, Jared M. Covell, Julieta Cruz Naranjo, Blaz Podgorsek, Peter C. Chen, Damien J. LaPar, Christopher E. Greenleaf, Division of Pediatric and Congenital Cardiac Surgery, Department of Cardiothoracic and Vascular Surgery, s Memorial Hermann Hospital, The University of Texas Health Science Center at Houston, Department of Cardiothoracic and Vascular Surgery, Memorial Hermann Hospital, The University of Texas Health Science Center at Houston

Perfusion

Published online on August 17, 2026

Abstract

Perfusion, Ahead of Print.
IntroductionDeep hypothermia (DH) has been widely adopted for cerebral and visceral protection during pediatric cardiac surgery, but concerns about perioperative complications remain. This meta-analysis aims to evaluate the impact of DH compared to ...