This article examines calls for the introduction of partisan politics into the District Assemblies system, which is the core institution in Ghana’s democratic decentralization program. I argue that in spite of constitutional provisions and an enabling legislation on the need for a ‘politically neutral’ District Assemblies system, this has not been the case, ironically partly due to the composition of the membership of the Assemblies as provided for in the 1992 Constitution and the unnecessary interferences by governments. This situation, the article notes, has undermined the effectiveness of the District Assemblies system. The article concludes by recommending certain measures that must be put in place if the situation is to be arrested and ensure the attainment of the goals of the District Assemblies system.