This paper is an ethnomusicological and media studies collaborative study that discusses the politics of representation on media health images, especially HIV/AIDS in Africa, and how a South African AIDS support group and choral ensemble offers a counter-narrative to the images that are seen in the Western media. Using ethnographic data on the group’s organization, music events, and interviews with choir members, we argue that Siphithemba Choir’s story is a narrative of self-representation that subverts the appropriation of their story by the scientific community, and counters the helpless image of HIV-infected individuals that often comprise the face of HIV/AIDS in Africa in the mainstream media.