To better understand the behavioral characteristics and the factors associated with high risky behaviors among men who have sex with men and women (MSMW) with different orientation.

We analyzed data from cross-sectional survey of 600 MSMW in two large cities in China. Participants need to complete the questionnaire and receive blood test.

Overall, human immunodeficiency virus (HIV) prevalence was 26%. In multivariable analysis of risk factors for unprotected anal intercourse in the past six months, factors associated with unprotected vaginal intercourse (UVI) were as follows: gay identified orientation, having anal sex with boyfriend, having multiple male partners, and never or sometimes using condom in vaginal intercourse. In multivariate analyses of risk factors for UVI in the past 12 months, factors associated with UVI were as follows: non-gay identified MSMW, having multiple male partners, having multiple female partners, and never or sometimes using condom in anal intercourse.

This study revealed the high prevalence of HIV and risky sexual behaviors.